I'm assuming you're talking about the first fuel filter past the fuel tank; the one mounted on the bulkhead forward of the fuel tank. It's normally referred to as "the primary fuel filter"; the filter housing unscrews from the filter head, that's where the fuel lines enter and exit. The filter head is bolted to the bulkhead. When new, that housing can be really tight and a bear to loosen. My housing has a drain plug which can be removed to drain the fuel before removing the housing.
My first R21EC was a 2009 model; one of the first to come with a primary fuel filter. At about 25 hours of engine operation, the engine would stop. I'd drain the housing; it'd start, run awhile and then stop. Then, I changed the filter which was somewhat dirty. That cured the problem.
Later, I changed the secondary filter, the one on the engine. It was perfectly clean as one would expect if the primary filter was doing its job properly.