ALL permanent antifreeze is Ethylene Glycol + Water in a 50:50 mixture...
The only difference is the anti-corrosion and water pump lubricant additives...
We will skip the water pump lubes as they are non controversial...
The classic anti-corrosion additive is a light metal such as Sodium Silicate, or a xxPhosphate or xxBorate, etc... These are Yellow, Blue, or Green colored antifreezes... i.e original PRESTONE green, etc... These have always had the recommendation to change every 2 years or 50,000 miles...
When automakers wanted to go to extended life products they developed the organic acid based anti-corrosion product that they claimed would go 5years or 150,000 mile, to replace the shorter life Silicate-Phosphate-Borate inhibitors...
You can tell the organic acid based antifreeze because it is the day glo Orange colored antifreeze (regardless of brand)...
Actually, these are good products but some engine materials and some gaskets do not like this chemical... GM called this product Dex-Cool... All current GM engines are compatible with Dex-Cool (obviously)
Ford engines have some gasket issues with the organic based acid antifreeze and prohibits Dex-Cool...
GM ran into some Dex-Cool trouble with engines that had the radiator cap allow air into the system... When air (primarily oxygen) was present in the cooling system for extended periods the organic acid molecules broke down and turned into sludge...
My wife had a Blazer that clogged the heater core due to this - at 45 degrees North latitude that is an issue - due to Dex-Cool sludging ...
So the bottom line in my opinion is if you are adding coolant stick with the same color (not necessarily brand) and that will remove the anxiety... Coolants of the same color will always be compatible for mixing...
Change the coolant every 2 years and use the cheapest stuff you can find at the auto store - color is not a factor if you are flushing and filling with new antifreeze...